MEMBERS

 

Umut A. Gurkan, PhD

PostDoc, Harvard Medical School, Brigham and Women's Hospital, Harvard-MIT HST

Ph.D., Purdue University, Biomedical Engineering

B.S., Middle East Technical University, Mechanical Engineering

B.S., Middle East Technical University, Chemical Engineering

Assistant Professor

Case Biomanufacturing and Microfabrication Laboratory

Mechanical and Aerospace Engineering

Biomedical Engineering

Orthopedics

Case Western Reserve University

Advanced Platform Technology Center

Louis Stokes Cleveland Veterans Affairs Medical Center

Address: Glennan 616B, 10900 Euclid Avenue, Cleveland, OH, 44106

Phone: +1 (216) 368-6447

E-mail: umut@case.edu

Web: www.case-bml.net

Biosketch: Umut A. Gurkan is leading the CASE Biomanufacturing and Microfabrication Laboratory (CASE-BML) at Case Western Reserve University (CWRU). Inspired by modern advanced manufacturing methods, the primary focus of CASE-BML is developing micro/nano-scale technologies and biomanufacturing complex multiscale biological systems for blood disease research, cardiovascular medicine, orthopaedics, musculoskeletal research, and regenerative medicine.

Selected Awards:

  • Faculty Early Career Development Award, National Science Foundation, NSF CAREER (2016)

  • “Rising Star” Award, Biomedical Engineering Society – Cellular and Molecular Bioengineering and Advanced Biomanufacturing Divisions (2016)

  • Glennan Fellowship, CWRU University Center for Innovation in Teaching and Education (2015)

  • MIT Technology Review Innovator Under 35 Award - Turkey (2014)

  • Coulter-Case Translational Research Partnership Award (2014)

  • Clinical and Translational Science Collaborative Annual Pilot Award (2014)

  • Case School of Engineering Research Award (2014)

  • Doris Duke Innovations in Clinical Research Award (2013)

  • Steve Garverick Memorial Innovation Incentive Award (2013)

  • Belcher-Weir Family Pediatric Innovation Award (2013)

  • Wyss Award for Translational Research, IEEE-Engineering in Medicine and Biology Society (2011)

  • Partners in Excellence Award for Outstanding Community Contributions (2011)

  • Geddes-Laufman-Greatbatch Outstanding Graduate Student Award (2009)

  • Top Dissertation Proposal Award, Purdue University (2009)

 

 

Graduate Students

Muhammad Noman Hasan

M.S., The University of Akron, Mechanical Engineering

B.S., Bangladesh University of Engineering and Technology, Mechanical Engineering

PhD candidate

E-mail: mnh38@case.edu

Biosketch: Muhammad Noman Hasan received his Bachelor of Science in Mechanical Engineering from Bangladesh University of Engineering and Technology, Bangladesh & Master of Science in Mechanical Engineering from The University of Akron, USA in 2009 and 2014, respectively. His undergraduate work focused on computational fluid dynamics and heat transfer for convective heat transfer. The research was focused on convective heat transfer within complex enclosure. His MS work focused on numerical analysis of droplet and continuous filament deformation for direct print systems. In fall 2014, he has joined CASE-BML in CWRU as a PhD Student. He is a member of the American Society of Mechanical Engineers (ASME). Noman has published 5+ papers in peer-reviewed journals.

Google Scholar Citations: http://scholar.google.com/citations?hl=en&user=kReBgDwAAAAJ

Erdem Kucukal

M.S., Case Western Reserve University, Mechanical and Aerospace Engineering
B.S.,
Kocaeli University, Mechanical Engineering

PhD student

E-mail: exk238@case.edu

Biosketch: Erdem Kucukal received his Bachelor of Science and Master of Science degrees in Mechanical Engineering from Kocaeli University, Turkey and Case Western Reserve University, USA in 2010 and 2015, respectively. He has been involved in the studies of several computational heat transfer projects as well as the use of PEM fuel cell technology in motorized vehicles for his undergraduate thesis work. His master’s work primarily focused on the numerical & experimental investigations of fluid flow within a hydrocyclone separator by means of Particle Image Velocimetry (PIV) and Computational Fluid Dynamics. In Spring 2015, he joined CASE-BML in CWRU as a PhD student. Some of his research interests include microfluidics, micro-PIV, CFD, biofluids, and applied math.

Yuncheng Man

B.S., Dalian University of Technology, Mechanical Engineering

PhD student

E-mail: yxm278@case.edu

Biosketch: Yuncheng Man received his Bachelor of Science degree in Mechanical Engineering from Dalian University of Technology, China in 2016. His undergraduate work was focused on microfabrication, especially on fabricating microsensors for electrochemical detection. In fall 2016, he has joined CASE-BML in CWRU as a direct PhD student. His current research focus is on microfabrication, microfluidics, and biomedical devices.

Mark Lewandowski

B.S., Case Western Reserve University, Mechanical and Aerospace Engineering

MS student

E-mail: mark.lewandowski@case.edu

Biosketch: Mark Lewandowski received his Bachelors of Science in Mechanical Engineering from Case Western Reserve University in the spring 2016 and is currently working towards his masters in the BS/MS program. Mark joined CASE-BML in the fall of 2015 and has been developing a portable syringe pump and portable imaging system for micro-fluidic chips. Mark is interested in the design of medial devices, especially those which leverage mechanical properties of cells, bio-markers, tissue, etc...

 

Postdoctoral Researchers

Arwa Fraiwan, PhD

Ph.D., State University of New York-Binghamton, Electrical Engineering
M.S., Jordan University of Science and Technology, Electrical Engineering
B.S., Jordan University of Science and Technology, Electrical Engineering

Postdoctoral Research Associate

E-mail: axf311@case.edu 

Biosketch: Arwa Fraiwan received her Ph.D. in Electrical Engineering from the State University of New York at Binghamton in 2016, During her PhD study she worked on the development of portable, low cost and disposable power supplies for powering biosensing platforms in resource-limited environments using paper-based microbial fuel cells. She has published 15 journal articles and 15 refereed conference proceedings. Her research interests include biofuel cells, and the development of affordable point-of-care biosensing and diagnostic tools for use in low-resource settings. She joined CASE-BML in summer 2016.

Google Scholar Citations: https://scholar.google.com/citations?user=RluRLBUAAAAJ&hl

 

Visiting Scholars

Birnur Akkaya, PhD

PhD., Cumhuriyet University, Faculty of Science, Department of Chemistry, Biochemistry
M.S., Cumhuriyet University, Faculty of Science, Department of Chemistry, Biochemistry
B.S., Hacettepe University, Faculty of Science, Department of Chemistry

Visiting Scholar, TUBITAK Fellowship

E-mail: bxa185@case.edu

Biosketch: Birnur AKKAYA received her Master of Science and Doctor of Philosophy in Biochemistry from Cumhuriyet University, TURKEY in 2005 and 2009, respectively. Her Master of Science and Doctor of Philosophy theses are focused on Bioaffinity Chromatography by using batch and continuous system which was supported by Prof. Dr. Adil Denizli at Hacettepe University Department of Biochemistry. Birnur also did research on Protein Purification, Enzymology, Metalloproteins, Preparation of Biodegredable materials. After Ph.D., she studied Microbial and Biochemical Technology which was supported by Prof. Dr. Ali Fazil Yenidunya at Cumhuriyet University Department of Molecular Biology and Genetics. She has published 16 papers in peer reviewed journals. In fall 2016, she has joined CASE-BML in CWRU as a visiting scholar supported by a TUBITAK (Scientific and Technological Research Council of Turkey) fellowship.

 

 

Interns

Grace Gongaware

Scientific Art Intern

Visual Design Artist at MIM Software

E-mail: ggongaware@student.cia.edu

Biosketch: Grace Gongaware was a student at the Cleveland Institute of Art where she majored in Biomedical Art. As a biomedical illustrator, her goal is to communicate scientific subject matter visually. Through her studies she has created works under an array of scientific fields, including zoology, human anatomy, histology, anthropology, botany, and entomology.

Courtney Fleming

Scientific Art Intern

E-mail: cefleming@student.cia.edu 

Biosketch: Grace Gongaware is a current student at the Cleveland Institute of Art where she is majoring in Biomedical Art. As a biomedical illustrator, her goal is to communicate scientific subject matter visually. Through her studies she has created works under an array of scientific fields, including zoology, human anatomy, histology, anthropology, botany, and entomology.

 

 

Lab Alumni

Yunus Alapan, PhD

PhD, Case Western Reserve University, Mechanical and Aerospace Engineering (2016)

M.S., Yildiz Technical University, Mechanical Engineering

B.S., Yildiz Technical University, Mechanical Engineering

Dissertation Title: Microfabricated Systems Integrated with Biomolecular Probes for Cell Mechanics

Current Position: Postdoc at Max Planck Institute for Intelligent Systems, Humboldt Fellow

E-mail: alapan@is.mpg.de

Google Scholar Citations: https://scholar.google.com/citations?user=H7GJhLwAAAAJ

Ryan Ung, MS

M.S., Case Western Reserve University, Biomedical Engineering (2016)

B.S., Case Western Reserve University, Biomedical Engineering (2015)

Thesis Title: The Design, Fabrication, and Testing of a Point of Care Device for Diagnosing Sickle Cell Disease and Other Hemoglobin Disorders

Current Position: Technical Service Engineer at Epic

E-mail: ryan.ung@case.edu

Myeongseop (James) Kim, MS

M.S., Case Western Reserve University, Mechanical and Aerospace Engineering (2016)

B.S., Cedarville University in Ohio, Mechanical Engineering

Thesis Title: Micro-Gas Exchanger for Oxygen Tension Control in Biological Microfluidic Systems

Current Position: Researcher at Agency for Defense Development in South Korea

E-mail: mykms0321@naver.com

 

Past Members

Ping He, MD, PhD

MD, School of Medicine, Zhejiang University
M.S., School of Medicine, Fudan University
Ph.D., School of Medicine, Fudan University


Sr. Research Associate, Lab Manager

E-mail: pxh36@case.edu

Biosketch: Dr. Ping He received her MD in School of Medicine, Zhejiang University, China. She received her Master degree and PhD degree from School of Medicine of Fudan University in Shanghai, China. Her Master study was Molecular Biology and gene engineering. Her PhD study was Gene therapy of cancer. She has 15+ years of experience in clinic as a physician in China. She also has many years of work experience on bone biology, molecular cardiology, and biomedical engineering at Case Western Reserve University and Cleveland Clinic. She joined CASE-BML in summer of 2014 as a Senior Research Associate & Lab Manager.

Ceonne Kim

B.A., Case Western Reserve University, Biology and Psychology

Clinical Research Assistant

E-mail: cxk223@case.edu

Biosketch: Ceonne received a Bachelor of Art degree in Biology and Psychology from Case Western Reserve University in 2014. During her undergraduate years, she worked both in a basic science laboratory and in clinical research, focusing on cancer biology and sickle cell diseases. She joined CASE-BML in the summer of 2014 to continue sickle cell research. Ultimately, she plans to pursue her career in medicine.

Anima Adhikari

B.S., George Mason University, Biology

Clinical Research Assistant

E-mail: axa781@case.edu 

Biosketch: Anima received a Bachelor of Science degree in Biology from George Mason University in Virginia. During her undergraduate years, she worked in Molecular and Microbiology lab, focusing on the molecular mechanisms of the nematode Caenorhabditis elegans. She joined CASE-BML in summer of 2015.

Tolulope “Tolu” Rosanwo

B.A., University of Chicago, Biological Sciences

Research Assistant

E-mail: tor4@case.edu  

Biosketch: Tolulope “Tolu” Rosanwo received her BA in Biological Sciences from the University of Chicago in 2014. Her undergraduate work focused on the role of Krüppel-Like Factor 1 in early erythroid differentiation. In July 2014, Tolu matriculated into CWRU School of Medicine, and she joined CASE-BML in CWRU in early 2015. Tolu is a member of the American Society of Hematology (ASH), a recipient of the ASH Minority Medical Student Award, and awardee of the National Heart, Lung and Blood Institute Internship for the summer of 2015.

Collin Krebs

B.S., Ohio State University, Pharmaceutical Sciences

Current Position: MD Student at University of Toledo

E-mail: jck124@case.edu

Biosketch: Collin was a graduate student at Case Western Reserve University pursuing a Masters Degree in Medical Physiology. He received a Bachelor of Science degree in Pharmaceutical Sciences from The Ohio State University in 2013. He is currently applying to medical schools in hopes of one day becoming a practicing physician.

Kaustav Bera

Undergraduate Student

E-mail: kaustav0bera@gmail.com 

Biosketch: Kaustav is a senior year student pursuing combined B.Tech/M.Tech degree in Biotechnology and Biochemical Engineering and minor in Chemical engineering at Indian institute of Technology Kharagpur, India. He joined CASE-BML as an exchange scholar (Khorana Program for Scholars, Indo-US Science and Technology Forum) and is developing a microfluidic rapid diagnostic system based upon RBC deformability. He likes working in interdisciplinary area involving biology and aspires to become a biomedical entrepreneur after his PhD.

Megan Romelfanger

Undergraduate Student

E-mail: mmr81@case.edu

Biosketch: Megan Romelfanger is a second year Biomedical Engineering student at Case Western Reserve University. She is specializing in Biomechanics with a minor in Mechanical Engineering. Ultimately, she plans to pursue a career in the Biomedical Engineering industry. She joined the CASE-BML in the Spring of 2014.

Yumi Matsuyama

Undergraduate Student

E-mail: yxm128@case.edu 

Biosketch: Yumi is a third year Mechanical Engineering student at Case Western Reserve University. Her past lab experiences were in the Department of Hematology and Oncology, and the Department of Ophthalmology. She joined the CASE-BML in the summer of 2014, and is planning on pursuing her masters at Case Western Reserve.

 

Aaron Tam

Undergraduate Student

E-mail: act48@case.edu 

Biosketch: Aaron Tam is currently a fourth year mechanical engineering student at CWRU. He is pursing a B.S. degree with an expected graduation date of May 2016. He joined CASE-BML in the Summer of 2015.

 

Kayla E. Gray

Undergraduate Student

E-mail: Kayla.Gray@case.edu

Biosketch: Kayla Gray is an undergraduate research student currently pursuing her Chemical Biology and Theater degrees at Case Western Reserve University. She has worked in a variety of lab settings for the past seven years with experience ranging from biochemistry to neurology to biomedical engineering. She is currently in the process of applying to medical schools with aspirations in clinical research.

Recent Publications: Belle V, Anka A, Cross N, Thompson Paul, Mott E, Sharmaa R, Gray K, Zhang R, Xu Y, Sun J, Flask CA, Oleinick NL, Dean D: Dynamic Contrast Enhanced-Magnetic Resonance Imaging (DCE-MRI) of Photodynamic Therapy (PDT) Outcome and Associated Changes in the Blood-Brain Barrier Following Pc 4-PDT of Glioma in an Athymic Nude Rat Model. SPIE, Proceedings Photonics West 2012, 8207(82074T):1-9, 2012.

Rishe Sivagnanam

Undergraduate Student

E-mail: rxs621@case.edu

Biosketch: Rishe Sivagnanam is a second year Biomedical Engineer at Case Western Reserve University. He is specializing in Biomechanics with a minor in Mechanical Engineering. He has previously worked at the Cleveland Clinic in the Stem Cell Biology/Regenerative Medicine Lab. His eventual goal is to go into the biomedical engineering industry.

Alexander Weber

Undergraduate Student

E-mail: weber.594@osu.edu

Biosketch: Alexander Weber is currently pursuing a Bachelor of Science degree in Biomedical Engineering at The Ohio State University with an expected graduation date of May 2015. He worked at CWRU as a summer 2013 undergraduate research student.

Mahmut Kamil Aslan

B.S., Bilkent University, Electrical and Electronics Engineering

Graduate student

E-mail: mka43@case.edu

Biosketch: Mahmut Kamil Aslan received the B.S. degree with honors in Electrical and Electronics Engineering Department from Bilkent University, Ankara, Turkey, in 2012. He worked at CASE-BML in Spring 2013. His current research interests include digital image processing, tissue engineering and medical imaging.

Paul Blumenkopf

Undergraduate Student

B.S., Case Western Reserve University, Mechanical Engineering

Biosketch: Paul worked on computer aided design and microfabrication at CASE-BML in 2013.

Current Position: Equity Engineering Group

Ismail Sayin

M.S., Case Western Reserve University, Biology

B.S., Middle East Technical University, Molecular Biology

PhD student

E-mail: ixs115@case.edu

Biosketch: Ismail is a PhD student in Biology Department at Case Western Reserve University. His current research focus is on application of micro/nano technologies in understanding endothelial cell biology in physiological and disease states.

David Lin

Undergraduate Student

E-mail: dyl16@case.edu

Biosketch: David Lin is currently a first year biomedical engineering student at Case Western Reserve University. He is specializing in computational analysis with a minor in computer science, and is pursuing a BS degree at CWRU. He joined CASE-BML in the Spring of 2014.

Richang Shen

Undergraduate Student (Senior Design)

E-mail: rxs580@case.edu

Biosketch: Richang Shen is a current senior Mechanical Engineering student at Case Western Reserve University. He has previously worked at Steris Corporation as a co-op student and is conducting his senior design project on 3D-printing for microfluidic chips at CASE-BML.

 

Zhenni Zhang

Undergraduate Student

E-mail: zxz222@case.edu

Biosketch: Zhenni Zhang is pursuing Bachelor of Science degree in Mechanical Engineering at Case Western Reserve University. She is expected to graduate May of 2017. She started her first research experience at CASE-BML as of Fall 2013.

 

Junior Researchers

Asya Akkus

Middle School Student

E-mail: asyasroom@gmail.com

Biosketch: Asya Akkus is a student at Stanford University online middle school. She is strongly interested in biosciences and physics. Asya purses a number of extracurricular activities including piano performance, Latin, and the study of formal logic. http://www.youtube.com/watch?v=dj8k-ayVH9Q

Kevin Callanan

High School Student

E-mail: kcallanan17@student.ignatius.edu

 

 

 

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